Semnan University of Medical Sciences

Research and Technology Vice Chancellor

Nassaji, Mohammad and Rahbar, Nahid and Ghorbani, Raheb and LAVAF, Sabahat (2008) The role of brucella infection among women with spontaneous abortion in an endemic region. Journal of the Turkish German Gynecology Association. pp. 20-23.

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    Objective: Brucella infection in animals is associated with high incidence of abortion but in the human, there are controversies about the role of brucellosis in spontaneous abortion. Brucellosis is endemic in Iran. Since many causes of abortion are undiagnosed, this study has been designed for the evaluation of a possible association between the previous maternal brucella infection and spontaneous abortion. Materials and Methods: In this study 81 women with spontaneous abortion were considered as the case group and 105 women with normal pregnancy outcome as the control group. IgG and IgM antibody were measured by enzyme-linked immunosorbent assay method in both groups. IgG or IgM levels equal to or greater than ten were considered to be positive. Results: Both groups were matched on the basis of age, number of previous pregnancies and abortion, gestational age and consumption of unpasteurized cheese, 6.2% of the case group and 13.6% of the control group had positive IgG titer (IgG ≥10). In both groups IgM was negative (IgM <10). There was no significant relationship between the brucella antibody and spontaneous abortion. There was a significant relationship between raw milk consumption and spontaneous abortion (OR=6.31). Discussion: This study showed that the brucella seropositivity is no more common in women with spontaneous abortion than in normal pregnancy.

    Item Type: Article
    Subjects: R Medicine > R Medicine (General)
    Divisions: Faculty of Medical Sciences > School of Medicine
    Depositing User: Mr Vahab Moshtaghi
    Date Deposited: 14 Jan 2017 08:26
    Last Modified: 14 Jan 2017 08:26

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