Semnan University of Medical Sciences

Research and Technology Vice Chancellor

Fatemi, Reza and Alizadeh AmirH, Mohammad and Derakhshan, Faramarz and Mousavi, Shahrokh and Zahmatkesh, Mehrdad and Shivarani, Sepideh and Nemati Malek, Fatemeh and Maserat, Elham and Zali, MR (2009) Colorectal stenting for management of acute malignant bowel obstruction in advanced colorectal cancer in iran. Asian Pacific Journal of Cancer Prevention. pp. 739-742.

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    Introduction: Enteral stenting is used increasingly as a palliative treatment of gastrointestinal malignant ornon malignant obstructions. This aim of this study was to evaluate the role of endoscopic stent implantation forpalliation of acute colorectal cancer obstruction in critical patients. Methods: This study was performedprospectively with 8 patients suffering clinical manifestations of acute bowel obstruction with severe co-morbiddiseases that caused them to be inoperable. They were treated by semi-elective stent insertion after primaryresuscitation. Gentle dilation of stricture with balloon or buginage was performed under fluoroscopy andcolonoscopy in gastrointestinal ward without complete preparation. Then an uncovered self-expanding metalstent was inserted over guide wire in the location of the tumor. Results: Endoscopic stent implantation could besuccessfully performed in six patients. In early days after stent insertion; general condition of patients graduallyimproved, and symptoms of acute obstruction was relieved. In two of the cases stent was inserted with difficultydue to very tortuous and complex strictures. Complications of stenting in this study were very rare. Displacementof stent after successful insertion was not seen . Of our studied patients, two died after 2 months, one after 4months and three of them after 7-8 months. The cause of death in these patients was advanced metastatic lesionin liver, lung, bone and severe underlying disease such as heart failure. Conclusion: Endoscopic stent implantationseems to be an effective and safe palliative approach for management of emergency conditions of acute colonicobstruction in inoperable patients with advanced colorectal cancer. Keywords colorectal cancer; self expanding metal stents; constriction

    Item Type: Article
    Subjects: R Medicine > R Medicine (General)
    Divisions: Faculty of Medical Sciences > School of Medicine
    Depositing User: Mr Vahab Moshtaghi
    Date Deposited: 24 Dec 2016 07:35
    Last Modified: 24 Dec 2016 07:35

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