Semnan University of Medical Sciences

Research and Technology Vice Chancellor

Rahbar, Nahid and Asgharzadeh, Neda and Ghorbani, Raheb (2012) Effect of omega-3 fatty acids on intensity of primary dysmenorrhea. International Journal of Gynecology & Obstetrics, 117 (1). pp. 45-47. ISSN 00207292

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    OBJECTIVE:To examine whether dietary supplementation with omega-3 fatty acids relieved symptoms of primary dysmenorrhea. METHODS:Women aged 18-22 years with primary dysmenorrhea were enrolled in a double-blind crossover study. Women assigned to group 1 (n=47) received 1 omega-3 capsule daily for 3 months, followed by placebo for 3 months. Women in group 2 (n=48) received placebo for 3 months, followed by omega-3 for 3 months. A washout period was performed in both groups. Participants used 400mg of ibuprofen as a rescue dose if severe menstrual pains were experienced. RESULTS:A marked reduction in pain intensity was observed after 3 months of treatment with omega-3 fatty acids (P<0.05). Women who received omega-3 fatty acids required fewer rescue doses than women who received placebo (P<0.05). The mean numbers of ibuprofen tablets used after 3 months with omega-3 fatty acids were 4.3±2.1 (group 1) and 3.2±2.5 (group 2); the mean numbers of tablets used after 3 months of placebo were 5.3±2.2 (group 1) and 6.0±2.6 (group 2) (P=0.001 for both). CONCLUSION:Supplementation with omega-3 fatty acids reduced the symptom intensity of primary dysmenorrhea. Supplementation efficacy was sufficient to decrease the ibuprofen rescue dose. Copyright © 2011 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

    Item Type: Article
    Subjects: R Medicine > R Medicine (General)
    Divisions: Faculty of Medical Sciences > School of Medicine
    Depositing User: Mr Vahab Moshtaghi
    Date Deposited: 26 Nov 2016 07:38
    Last Modified: 26 Nov 2016 07:38

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