Semnan University of Medical Sciences

Research and Technology Vice Chancellor

Talimkhani, A. and Abdollahi, I. and Mohseni-Bandpei, M.A. and Ehsani, F. and Khalili, S. and Jaberzadeh, S. (2019) Research paper: Differential effects of unihemispheric concurrent dual-site and conventional tDCS on motor learning: A randomized, sham-controlled study. Basic and clinical neuroscience, 10. pp. 59-71. ISSN 2008-126X

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    Abstract

    Introduction: Based on the literature, unihemispheric concurrent dual-site anodal transcranial Direct Current Stimulation (a-tDCSUHCDS) of primary Motor cortex (M1) and Dorsolateral Prefrontal Cortex (DLPFC) would be more efficient than conventional a-tDCS of M1 to induce larger and longer-lasting M1 corticospinal excitability. The main objective of the present study was to compare the effects of a-tDCSUHCDS and conventional M1 a-tDCS on the extent and durability of the motor sequence acquisition in healthy individuals. Methods: In this randomized sham-controlled study, healthy volunteers were randomly divided into three groups: experimental (a-tDCSUHCDS), control (M1 a-tDCS), and sham stimulation groups. The participants practiced serial response time task over three consecutive days when they simultaneously received a-tDCS. Using the skill measure, we assessed motor learning up to 4 weeks after the completion of experimental conditions. Results: Data analysis revealed that all groups exhibited the improved trend over the training course (P<0.001). There were no significant differences in skill acquisition among groups at post-intervention (P>0.05), while a significant improvement was observed between experimental and sham group at the retention time (P<0.05). Moreover, there were no significant differences between the control and two other groups with regard to the retention time (P>0.05). Conclusion: These results revealed a significant increase in the skill acquisition by a-tDCSUHCDS technique with regard to retention issue, which could be a valuable finding in neuro-rehabilitation field. © 2018 Iran University of Medical Sciences.

    Item Type: Article
    Subjects: R Medicine > R Medicine (General)
    R Medicine > RA Public aspects of medicine
    Divisions: Faculty of Medical Sciences > School of Medicine
    Depositing User: Admin User
    Date Deposited: 18 Mar 2019 11:54
    Last Modified: 18 Mar 2019 11:54
    URI: http://eprints.semums.ac.ir/id/eprint/1530

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