Semnan University of Medical Sciences

Research and Technology Vice Chancellor

Rahbar, Nahid and Faranoush, Mohammad and Ghorbani, Raheb and Sadr Alsadat, Bahare (2015) Screening of von Willebrand disease in Iranian women with menorrhagia. Iranian Red Crescent medical journal, 17 (1). pp. 1-4. ISSN 2074-1804

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    Background: Menorrhagia is a common health problem in women, particularly those with bleeding disorders. Little is known about the course of menorrhagia or other bleeding symptoms in women with the most common congenital bleeding disorder, von Willebranddisease (vWD). Objectives:The aim of this study was to estimate the prevalence of vWD in women with diagnosed menorrhagia. Materials and Methods: In this cross-sectional study, a total of 460 consecutive patients, presenting menorrhagia, were analyzed. The initial screening and confirmation tests for the diagnosis of vWD included determination of prothrombin time (PT), partial thromboplastin time (PTT), bleeding time (BT), fibrinogen, factor VIII, vWF antigen, and vWF activity. A questionnaire was filled for every patient. The data were then analyzed using the SPSS software. Results: Mean age of our patients was 32.5 ± 10.6 years. The level of von Willebrand factor in 22.5% and von Willebrand activity in 19.6% of patients was abnormal. The prevalence of vWD among patients with menorrhagia was 24%. Conclusions: The high prevalence of vWD among our patients was the same as other previous reports, suggesting low awareness about this disease and under diagnosis of mild cases. Keywords: Menorrhagia; Von Willebrand Disease; Von Willebrand Factor

    Item Type: Article
    Subjects: R Medicine > R Medicine (General)
    Divisions: Faculty of Medical Sciences > School of Medicine
    Depositing User: Mr Vahab Moshtaghi
    Date Deposited: 11 Sep 2016 09:13
    Last Modified: 11 Sep 2016 09:13

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