Semnan University of Medical Sciences

Research and Technology Vice Chancellor

Mahmoodnia, Leila and Beigrezaei, Sara and Tamadon, Mohammad Reza and Jafari, Tina and Kafeshani, Marzieh and Mahmoodi, Fatemeh and Hasanpour Dehkordi, Ali and Amiri, Masoud (2018) The relationship between serum ghrelin levels and bone metabolism markers and severity anemia in non-diabetic hemodialysis patients; a pilot study. Journal of Nephropathology, 7 (1). pp. 32-36. ISSN 2251-8363

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Abstract

Background: Chronic kidney disease (CKD) is a consequence of progressive and irreversible destruction of nephrons, mainly due to uncontrolled diabetes mellitus and high blood pressure. Ghrelin is a peptide hormone which could play a substantial role in hunger sensation, may increase body fat percentage and might adjust the long-term body weight and is mostly secreted in the stomach. Objectives: This study aimed to evaluate the relationship between ghrelin levels and various biochemical and demographic indices in a group of non-diabetic hemodialysis patients. Patients and Methods: Around 39 non-diabetic patients undergoing hemodialysis in Hajar hospital at Shahrekord city were enrolled. Results: The mean age of patients was 57.10±20.20 years. Their mean weight was 56.65 ±16.25 kg. Their hemoglobin level mean was 10.43±1.84 g/dL. The serum ghrelin level had a positive but not significant correlation with the age, dialysis quality, dosage, calcium level, alkaline phosphatase (ALP), parathormone, vitamin D and hemoglobin in these patients. Conclusions: More studies in this subject of hemodialysis patients to define the exact role of ghrelin in hemodialysis patients are recommended. Key words: Ghrelin, Bone metabolism, Inflammation, Anemia, Hemodialysis

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medical Sciences > School of Medicine
Depositing User: Mr Vahab Moshtaghi
Date Deposited: 04 May 2018 23:24
Last Modified: 23 May 2018 01:27
URI: http://eprints.semums.ac.ir/id/eprint/1399

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