Semnan University of Medical Sciences

Research and Technology Vice Chancellor

Yousefzadeh, Samira and Matin, Atiyeh Rajabi and Ahmadi, Ehsan and Sabeti, Zahra and Alimohammadi, Mahmood and Aslani, Hassan and Nabizadeh, Ramin (2018) Response surface methodology as a tool for modeling and optimization of Bacillus subtilis spores inactivation by UV/ nano-Fe 0 process for safe water production. Food and Chemical Toxicology, 114. pp. 334-345. ISSN 02786915

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One of the most important aspects of environmental issues is the demand for clean and safe water. Meanwhile, disinfection process is one of the most important steps in safe water production. The present study aims at estimating the performance of UV, nano Zero-Valent Iron particles (nZVI, nano-Fe0), and UV treatment with the addition of nZVI (combined process) for Bacillus subtilis spores inactivation. Effects of different factors on inactivation including contact time, initial nZVI concentration, UV irradiance and various aerations conditions were investigated. Response surface methodology, based on a five-level, two variable central composite design, was used to optimize target microorganism reduction and the experimental parameters. The results indicated that the disinfection time had the greatest positive impact on disinfection ability among the different selected independent variables. According to the results, it can be concluded that microbial reduction by UV alone was more effective than nZVI while the combined UV/nZVI process demonstrated the maximum log reduction. The optimum reduction of about 4 logs was observed at 491 mg/L of nZVI and 60 min of contact time when spores were exposed to UV radiation under deaerated condition. Therefore, UV/nZVI process can be suggested as a reliable method for Bacillus subtilis spores inactivation. KEYWORDS: Bacillus subtilis spores; Central composite design; Disinfection; Response surface methodology; UV radiation; Zero-valent iron

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medical Sciences > School of Medicine
Depositing User: Mr Vahab Moshtaghi
Date Deposited: 30 Apr 2018 14:04
Last Modified: 23 May 2018 09:56

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