Bitarafan-Rajabi, Ahmad and Rafati, Mehravar and Rouhani, Hemmatollah and Noori-Asl, Mahsa and Farhood, Bagher and Ahangari, HadiTaleshi (2017) Assessment of the scatter correction procedures in single photon emission computed tomography imaging using simulation and clinical study. Journal of Cancer Research and Therapeutics. ISSN 0973-1482
Full text not available from this repository.Abstract
BACKGROUND:Compton-scattered photons transfer incorrect spatial information. These photons are detected in used photo-peak energy window. In this study, three scatter correction procedures including dual-energy window (DEW), three energy window (TEW), and new approach were evaluated, and then the best procedure based on simulation and clinical conditions introduced. MATERIALS AND METHODS:In this study, simulation projections and three-dimensional nonuniform rational B-spline-based Cardiac-Torso phantoms were produced by GEANT4 application for emission tomography simulation code. For clinical study, 2-day stress/rest myocardial perfusion imaging (MPI) protocol was performed with 99m Tc-sestamibi for 46 patients. Image quality parameters including contrast, signal-to-noise ratio (SNR), and relative noise of the background (RNB) were evaluated. RESULTS:The simulation results showed that contrast values for DEW, TEW, and new approach were (0.45 ± 0.07, 0.5 ± 0.08, and 0.63 ± 0.09), SNR values (4.74 ± 0.94, 5.58 ± 1.08, and 6.56 ± 1.24), and RNB values (0.33 ± 0.06, 0.33 ± 0.07, and 0.33 ± 0.05), respectively. In clinical study, the contrast values for DEW, TEW, and new approach were 0.53 ± 0.03, 0.57 ± 0.07, and 0.62 ± 0.04 in rest MPI and were 0.52 ± 0.04, 0.57 ± 0.06, and 0.6 ± 0.05 in stress MPI, respectively. Moreover, for the rest images, the SNR values were 7.65 ± 1.9, 9.08 ± 2.2, and 10.2 ± 1.75 and for stress images were 7.76 ± 1.99, 9.12 ± 2.25, and 10.17 ± 2.04, respectively. Finally, RNB values for rest and stress images were 0.12 ± 0.03, 0.13 ± 0.03, and 0.13 ± 0.03, respectively. CONCLUSION:The simulation and the clinical studies showed that the new approach could be better performance than DEW, TEW methods, according to values of the contrast, and the SNR for scatter correction.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medical Sciences > School of Medicine |
| Depositing User: | Mr Vahab Moshtaghi |
| Date Deposited: | 25 Apr 2018 14:04 |
| Last Modified: | 15 May 2018 10:18 |
| URI: | http://eprints.semums.ac.ir/id/eprint/1250 |
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