Semnan University of Medical Sciences

Research and Technology Vice Chancellor

Malekzadeh, Masoud M. and Vahedi, Homayoon and Gohari, Kimiya and Mehdipour, Parinaz and Sepanlou, Sadaf G. and Ebrahimi Daryani, Nasser and Zali, Mohammad Reza and Mansour-Ghanaei, Fariborz and Safaripour, Alireza and Aghazadeh, Rahim and Vossoughinia, Hassan and Fakheri, Hafez and Somi, Mohammad H. and Maleki, Iradj and Hoseini, Vahid and Ghadir, Mohammad Reza and Daghaghzadeh, Hamed and Adibi, Payman and Tavakoli, Hamid and Taghavi, Alireza and Zahedi, Mohammad Javad and Amiriani, Taghi and Tabib, Masoud and Alipour, Zainab and Nobakht, Hossein and Yazdanbod, Abbas and Sadreddini, Masoud and Bakhshipour, Alireza and Khosravi, Ahmad and Khosravi, Pejman and Nasseri-Moghaddam, Siavosh and Merat, Shahin and Sotoudehmanesh, Rasoul and Barazandeh, Farhad and Arab, Peyman and Baniasadi, Nadieh and Pournaghi, Seyyed Javad and Parsaeian, Mahboubeh and Farzadfar, Farshad and Malekzadeh, Reza (2016) Emerging epidemic of inflammatory bowel disease in a middle income country: A nation-wide study from Iran. Archives of Iranian Medicine. pp. 1-14.

[img] PDF
Download (608Kb)


    BACKGROUND: The burden of inflammatory bowel disease (IBD) hasn't been reported in Iran. We aimed to estimate the prevalence and incidence of IBD and its trend in Iran at national and subnational level from 1990 to 2012. METHODS:We conducted a systematic review of English and Persian databases about the epidemiology of IBD. We also collected outpatient data from 17 provinces of Iran using almost all public and private referral gastroenterology clinics. Prevalence and incidence rate was calculated at national and subnational levels. The Kriging method was used to extrapolate provinces with missing data and GPR model to calculate time trends of rates at subnational level. RESULTS:We found 16 case series, two population-based studies, and two review articles. We collected 11,000 IBD cases from outpatient databases. Among them, 9,269 (84.26%) had ulcerative colitis (UC), 1,646 (14.96%) had Crohn's disease (CD), and 85 had intermediate colitis (IC). A total of 5,452 (49.56%) patients were male. Mean age at diagnosis was 32.80 years (CI: 13 - 61) for UC and 29.98 years (CI: 11 - 58) for CD. Annual incidences of IBD, UC, and CD in 2012 were 3.11, 2.70, and 0.41 per 100,000 subjects respectively. Prevalence of IBD, UC, and CD in 2012 were 40.67, 35.52, and 5.03 per 100,000 subjects respectively. The incidence of UC and CD showed a significant increase during the study period (P for trend < 0.05). CONCLUSIONS:The incidence and prevalence of IBD are increasing in Iran. Establishing a national IBD registry seems necessary for comprehensive care of IBD patients in Iran.

    Item Type: Article
    Subjects: R Medicine > R Medicine (General)
    Divisions: Faculty of Medical Sciences > School of Medicine
    Depositing User: Mr Vahab Moshtaghi
    Date Deposited: 02 Jul 2017 07:53
    Last Modified: 02 Jul 2017 07:53

    Actions (login required)

    View Item